Protecting Life and Integrity in Research Act of 2025
S. 987119th Congress

Protecting Life and Integrity in Research Act of 2025

Introduced in the SenateSen. Cindy Hyde-Smith (R-MS)32 sections · 2 min read
Version: is · Apr 20, 2026

Section 1. Short title

This Act may be cited as the Protecting Life and Integrity in Research Act of 2025.

(1) In general

No Federal department, agency, or office may conduct, fund, approve, or otherwise support any research involving human fetal tissue that is obtained pursuant to an induced abortion.

(2) Development of new, ethical cell lines

Subsection (a) does not limit the authority of the head of any Federal department, agency, or office, to develop or support the development of new, high-efficiency cell lines, including for the production of vaccines and genetic vectors, so long as the cell lines are not derived from human fetal tissue that is obtained pursuant to an induced abortion.

(3) Research involving human fetal tissue obtained after a miscarriage or stillbirth permitted

Any research of any Federal department, agency, or office on human fetal tissue obtained after a miscarriage or stillbirth shall be conducted or supported in accordance with section 498A of the Public Health Service Act (42 U.S.C. 289g–1).

(4) Definition

In this subsection, the term human fetal tissue has the meaning given such term in section 498A(g) of the Public Health Service Act (42 U.S.C. 289g–1(g)).

(b) Amendments to the PHSA limiting human fetal tissue research to tissue obtained after a miscarriage or stillbirth

Section 498A of the Public Health Service Act (42 U.S.C. 289g–1) is amended—

(1) in the section heading, by striking transplantation of fetal tissue and inserting human fetal tissue obtained after a miscarriage or stillbirth;

(2) by amending subsection (a) to read as follows:

(a) Establishment of program

The Secretary may conduct or support research on human fetal tissue obtained after a miscarriage or a stillbirth.

(3) in subsection (b)—

(A) in paragraph (1)(B), by inserting if the human fetal tissue is intended for transplantation, before the donation; and

(B) in paragraph (2)—

(i) by striking subparagraph (A); and

(ii) by redesignating subparagraphs (B) and (C) as subparagraphs (A) and (B), respectively;

(4) in subsection (c)(1)(B), by striking pursuant to a spontaneous or induced abortion or pursuant to and inserting after a miscarriage or; and

(5) by amending subsection (g) to read as follows:

(g) Definitions

In this section:

(1) Human fetal tissue

The term human fetal tissue means tissue or cells obtained from a dead unborn child pursuant to an induced abortion, a miscarriage, or a stillbirth.

(2) Miscarriage

The term miscarriage means the involuntary death of an unborn child who was carried in the womb for a period of less than 20 weeks.

(3) Stillbirth

The term stillbirth means the involuntary death of an unborn child who was carried in the womb for a period of 20 weeks or more.

(4) Unborn child

-The term unborn child has the meaning given such term in section 1841(d) of title 18, United States Code.

(c) Conforming repeal

Section 113 of the National Institutes of Health Revitalization Act of 1993 (42 U.S.C. 289g–1 note) is repealed.

(a) In general

Paragraph (1) of section 498B(c) of the Public Health Service Act (42 U.S.C. 289g–2(c)) is amended to read as follows:

(1) solicit or knowingly acquire, receive, or accept a donation (excluding any transfer for purposes of autopsy or burial) of human fetal tissue knowing that—

(A) a human pregnancy was deliberately initiated to provide such tissue; or

(B) the tissue was obtained pursuant to an induced abortion; or

(b) Conforming changes

Section 498B of the Public Health Service Act (42 U.S.C. 289g–2) is amended—

(1) by striking subsection (b);

(2) by redesignating subsections (c) through (e) as subsections (b) through (d), respectively; and

(3) in subsection (c), as redesignated—

(A) in paragraph (1), by striking (a), (b), or (c) and inserting (a) or (b); and

(B) in paragraph (2), by striking or (b)(3).

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